Irene Heinz Given and John LaPorte Given Professor of Pathology
A pioneer of the oncologic molecular pathology discipline as well as the systems pathology platform, Dr. Cordon-Cardo has helped establish a deeper understanding of the mechanisms of human cancers and new targets for cancer therapeutics, enhancing the vision of personalized medicine. A native of Spain, Dr. Cordon-Cardo earned his medical degree from the Autonomous University of Barcelona, Spain, in 1980 and his PhD in Cell Biology and Genetics from Cornell University Medical College in 1985.
An accomplished and internationally-recognized researcher, Dr. Cordon-Cardo is renowned for his studies on experimental pathology and molecular oncology. His analyses of multi-drug resistance and alterations of tumor suppressor genes in human cancer have led to extraordinary breakthroughs in the way scientists understand and investigate the progression of certain solid-tumor cancers. More recently, studies from his laboratory have linked adult stem cells and cancer, reporting the discovery of a subpopulation of tumor initiating cells with stem properties which are also related to chemoresistance and metastatic spread.
Dr. Cordon-Cardo has developed and implemented a novel “systems pathology” platform. This approach uses computational biology to form mathematical models of the interaction and behavior of cancer cells with the goal of determining clinical outcome. He is also the Principal Investigator on several National Cancer Institute (NCI)-funded grants, and has received uninterrupted NIH/NCI funding for the past 25 years. A prolific writer and speaker, Dr. Cordon-Cardo has lectured widely and is one of the “Highly Cited Authors” by the Institute of Scientific Information in the biomedical sciences, and one of the “Highly Influential Biomedical Researchers” (1996-2011 – one of the top 400 over 15,153,100 author identifiers, with h-index of 84) by the European Society for Clinical Investigation. Committed to educating the newest generation of scientists in his field, Dr. Cordon-Cardo has mentored over 70 investigators throughout his career.
Dr. Cordon-Cardo has received numerous awards in acknowledgement of his significant contributions to the field of pathology, including the Gold Medal of the Swedish Society of Physicians. He is a member on the Roll of Honour of the International Union Against Cancer, honorary member of the Spanish-American Medical and Dental Society, and received an honorary doctorate from the Universidad de Barcelona. He is also a member of the World Health Organization Collaborating Centers for Urologic Tumors, and the State Legislative Committee of the American Association for Cancer Research. He served as President for the Solid Tumor Chapter of the Association for Molecular Pathology, and member of the Review Committee for Cancer Centers and Research Programs of the NCI.
Recently recruited to the Icahn School of Medicine at Mount Sinai as Chairman for the Department of Pathology, Dr. Cordon-Cardo has outlined a broad vision that redefines the discipline of Pathology, placing it at the core of patient management and individualized medicine. He is expanding biorepositories and databases to enhance translational research, converting his vision into a reality. Dr. Cordon-Cardo was previously at Columbia University, where he served as Vice-Chair of Pathology, Professor of Pathology and Urology, and Associate Director for Infrastructure at the Herbert Irving Comprehensive Cancer Center. In addition, from 1987 to 2006, Dr. Cordon-Cardo was a faculty member in the Department of Pathology at Memorial Sloan-Kettering Cancer Center, where he created the Division of Molecular Pathology and served as its first Director, and move through academic ranks and was Professor of Pathology at Weill Cornell Medical College.