He obtained his MD degree by the University of Barcelona in 1983. He trained as a general and digestive surgeon at the Hospital de Sant Pau, Barcelona. His interest in translational cancer research lead him to a postdoctoral stay with Dr. Manuel Perucho the years 1989 and 1990. Back to Spain he spent 8 years at the Gastrointestinal Research Laboratory at the Hospital de Sant Pau where he focused his research in the molecular basis of pancreatic and colorectal cancer. Since 1998 he works at the Catalan Institute of Oncology where he has been Director of the Translational Research Laboratory until 2011. Since 2010 he is serving as Director of the Hereditary Cancer Program.
His main interest is the study of the genetic basis of gastrointestinal cancer focusing in novel technologies for the clinical management of patient at risk of developing GI Cancer. He is coauthor of more than 220 publications in international peer-reviewed journals. He has served as Vice-Director for Research and Innovation, Health Department, Catalan Government and he is currently the Director of the Bellvitge Biomedical Research Institute. He is co-founder of VCN Biosciences an spin-off aimed at developing new cancer therapies based on oncolytic adenoviruses.